Stroke Research & Therapy

The Role of Lipoprotein (a) in Intracranial Atherosclerotic Disease: A Hospital Based Cross Sectional Study from India

The atherosclerotic plaque develops due to the accumulation of lipids, inflammatory cells, smooth muscle cells, and extracellular matrix in the sub-endothelial space over time. Atherosclerotic plaques are mainly found at arterial bifurcations, branch points and vessel curvatures, whereas straight non branching arterial segments are generally spared. Stroke is a major cause of mortality and morbidity worldwide, with ischemic stroke being the predominant type (approximately 80%) found in stroke patients. With the current ageing population, the number of people suffering from stroke will inevitably escalate leading to increasing demand for more effective prevention, diagnosis and treatment strategies.

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